AUTOIMMUNE DISEASES CAUSED BY AN INFECTION?

[riclapaz]

And Also Xylitol (In this case used against oral biofilms)
http://www.ncbi.nlm.nih.gov/pubmed/19178100

PURPOSE:
The aim of the present study was to examine whether xylitol, at different concentrations, inhibits the formation of an experimental model of oral biofilm.
MATERIALS AND METHODS:
Biofilms of six bacterial species (Streptococcus mutans, Streptococcus sobrinus, Lactobacillus rhamnosus, Actinomyces viscosus, Porphyromonas gingivalis and Fusobacterium nucleatum) were prepared on hydroxyapatite (HA) discs according to the Zürich Biofilm Model. Xylitol was tested at two concentrations, 1% and 3%. At the end of their designated incubation times, some HA discs were destined for confocal laser scanning microscopy (CLSM) and the others were harvested using a sterile surgical instrument. Aliquots of harvested biofilms were diluted and plated onto specific media. After a 48-h anaerobic incubation at 37 degrees C, the colony-forming units (CFUs) were counted.
RESULTS:
CLSM images showed that only a small amount of isolated bacteria was observed on the surface of HA discs. Culture of harvested biofilms showed an inhibition in the growth of different species included in the biofilms.
CONCLUSIONS:
Xylitol has a clear inhibitory effect on the formation of the experimental biofilms. This study shows that xylitol is not only efficient in inhibiting the acid production of cariogenic bacteria, but also in preventing the formation of a multispecies biofilm; it confirms the relevance of the use of this polyol for the prevention of oral diseases caused by dental plaque.

Well, that's pretty interesting. Perhaps the reason some of us have issues with xylitol is that the mycoplasmas/biofilms react against it. Maybe that's one clue to those who have such infections: they have a reaction to xylitol???

I wonder if the coconut oil could be another clue?
_http://www.easihealth.co.za/wordpress/wp-content/uploads/downloads/2011/02/trials/Monolaurin.pdf

COCONUT OIL IN HEALTH AND DISEASE: ITS AND MONOLAURIN’S
POTENTIAL AS CURE FOR HIV/AIDS*
By
Dr. Conrado S. Dayrit**

HIV-AIDS Patients and the Coconut
According to Mary Enig(11), the AIDS organization, Keep Hope Alive, has documented several
HIV -AIDS patients whose viral load fell to as low as undetectable levels, when they took coconut
oil or ate coconut (half a coconut a day) or when they added coconut to their anti-HIV medication
(anti protease and/or antiretrovirals) that had previously not been effective. The amount of coconut
oil consumed (50 ml or 3 1/2 tablespoonfuls) or half of a coconut, would contain 20-25 grams of
lauric acid, which indicates that the oil is metabolized in the body to release lauric acid and/or
monolaurin.

The Monolaurin Trial on HIV-AIDS
The first clinical trial (pilot study) using Monolaurin for 6 months as monotherapy on 15 mv
patients was just completed (12). These 15 patients (Table 1) ages 21 to 38 years, 5 males and 10
females, were all regularly reporting to San Lazaro Hospital, the hospital for infectious disease of
the Department of Health. None of them could afford’ or ever received anti-HIV treatment. The
males averaged 58 k in weight (49 to 68 k) and the females, 54k (39 to 65 k). Seven showed
elevated liver enzymes (ALT and AST) and 12 had unexplained eosinophilia. Two patients had
high serum cholesterol and one had elevated triglyceride. No one had renal dysfunction. Their viral
load ranged from 1,960 to 1,190,000 except for one patient (#94-022B) whose load was too low to
3
count (below 400). This fact unfortunately was not determined before the random assignment of the
patients to the 3 treatment groups. The monolaurin used was 95% pure. It was given in capsules,
each containing 800 mg ML. The coconut oil was administered by tablespoonfuls.
The 3 treatment groups to which the 15 patients were randomly assigned were {Table II):
a) High Dose Monolaurin (HML): 7.2 grams (9 capsules) ML 3 time daily or about
22 grams daily
b) Low Dose Monolaurin (LML): 2.4 grams (3 capsules) ML 3 times daily or 7.2
grams daily.
c) Coconut oil (CNO): 15 ml 3 times daily or 45 ml daily. The ML content of this
dose is about the same as HML.
All patients were observed daily for any side effects. Baseline, 3-month and 6-month laboratory
examinations included: viral load (by PCR method), CD4 and CD8 counts (by-flow-cytometric
method), complete blood count, tests for liver function (ALT, AST), renal function (urea N and
creatinine), blood lipids (cholesterol, triglycerides, HDL) and body weight (k). Treatment benefit
was defmed as reduction in viral load and increase in CD4 count.

Tables II and III summarize the effects of the 3 treatment groups on the viral load, CD4 and
CD8 counts. On the 3rd month, 2 showed decreased viral count with HML, 2 with LML and 3 with
CNO for a total of 7 patients benefited. The other patients all had increased viral load. Patient #94-
022A continued to have undeterminable viral load and was excluded from the computation. On the
6th month, and end of the study. 8 of the 14 patients had decreased viral count, (2 of the 4 given
HML, 4 of the 5 given LML and 3 of the 5 given CNO). The decrease in viral count was, however,
significant only in 3 patients using the log Baseline-log 6th month ~ 0.5 criterion. Two of these
significant decreases were in the CNO group and one in the LML group.
The CD4. and CD8 counts (Table III) increased only in 5 patients and did not quite correlate
with the fall in viral load, decreasing even when the viral load fell and increasing when the viral
load rose. Patient #93006 had a steady viral load during the first 3 months but suffered a severe
secondary infection in the 5th and 6th month, which caused the HIV infection to worsen despite
fairly good CD4/CD8 response.

AIDS (CD4 less than 200) developed in 3 patients on the 3ni month of LML therapy (2 patients)
and CNO therapy (1 patient). The last mentioned patient (#86-001) died 2 weeks after the termination
of the study. The patient under LML, however, fared better; one (# 93028) recovered by the 6th
month. and the other (#95052) was showing improvement of both CD4 and CD8 counts at the end
of the study.
Eleven (11) subjects gained weight -from 1 k to 23 k -including the 2 who developed AIDS and
were recovering. The single AIDS fatality lost 6 k. The other 3 who failed to gain weight had
decreasing viral and rising CD4 counts.
4
About one-half of the subjects in this study complained of feeling of warmth and a greenish
hue to their urine (Table IV A), Both occurred at the beginning of the study and did not interfere
with its continuation. Another 3 subjects had flaring up of their acne.
There were 11 subjects with eosinophilia at the start and 7 subjects with some liver dysfunction
(Table 1). The treatment caused a rise of the eosinophilia in 7 of the II, and a rise in ALT/AST in 3
of the 7 (Table IVA).

The patients with normal liver and kidney functions showed no effect from the treatments.
At the beginning, 2 subjects had elevated cholesterol and another one had high serum triglyceride
(Table !VB). After 6 months, 4 patients had abnormal cholesterol and triglyceride, 3 had high
cholesterol only and 2 had high triglyceride only.

Conclusion from the Study
This initial trial confirmed the anecdotal reports that coconut oil does have an anti-viral effect
and can beneficially reduce the viral load of HIV patients.The positive anti-viral action was seen
not only with the monoglyceride of lauric acid but with coconut oil itself. This indicates that coconut
oil is metabolized to monoglyceride forms of C-8, C-IO, C- 12 to which it must owe its antipathogenic
activity.
More and longer therapies using monolaurin will have to be designed and done before the
defmitive role of such coco products can be determined. With such products, the outlook for more
efficacious and cheaper anti HIV therapy is improved.

Anti-pathogen Mechanism of Monotriglycerides of MCT
The fact dlat monolaurin’s activity is limited to lipid coated organisms (gram positive bacteria,
enveloped viruses) suggests strongly that the relatively short C-12, C-IO or C-8 [Icelandic scientists
have recently reported on the effectiveness of monocaprin (C-IO) against HIV virus] probably exert
their action on the lipid-layered coat or plasma membrane to destabilize it or even to cause its
rupture. If this mechanism proves correct, monolaurin (and monocaprin and monocapryliu) could
be bactericidal and could act synergistically with the present anti-HIV agents (the antiretrovirals
and protease inhibitors).

Reprise
With all the opprobrium cast against it, it bears repeating again and again that no evidence has
ever been presented to prove that coconut oil causes coronary heart disease in humans. All the
evidences presented have been in various species of animals who were given coconut oil alone
without the necessary dose of essential fats or PUFA that should be given, just like the essential
vitamins and minerals. On the contrary, the human epidemiologic evidence proves that coconut oil
is safe. Coconut eating peoples like the Polynesians (Table V) and Filipinos (Fig. I) have low
cholesterol, on the average, and very low incidence of heart disease.

 

[riclapaz]

Here in this article is more detailed:

_http://www.touroinstitute.com/natural%20bactericidal.pdf

Monolaurin, a monoester formed from lauric acid (mediumchain
fatty acids), has profound antiviral and antibacterial activity.
Recognition of the antimicrobial activity of the monoglyceride
of lauric acid (monolaurin) has been reported since 1966.
A large body of the research can be credited to Jon J. Kabara,
B.S., M.S., Ph.D., a professor emeritus of Michigan State University
in East Lansing.3 His early pioneer work focused on the
virucidal effects of monolaurin (Lauricidin,® Med-Chem Laboratories,
Inc., Galena, Illinois) on enveloped RNA and DNA
viruses. This work continues to be investigated by numerous
researchers because of the potential benefits related to food
preservation.
A recent study


Table 1. Lipid-Coated Bacteria Inactivated
by Monolaurin
• Listeria monocytogenes
• Helicobacter pylori (gram-negative)
• Hemophilus influenzae (gram-negative)
• Staphylococcus aureus
• Streptococcus agalactiae
• Groups A, B, F, and G streptococci
• Gram-positive organisms
• Gram-negative organisms if pretreated with a chelator


Table 2. Lipid-Coated Viruses Inactivated by
Monolaurin
• Human immunodeficiency virus HIV-1, HIV+
• Measles virus
• Herpes simplex virus-1
• Herpes simplex virus-2
• Herpes viridae (all)
• Human lymphotropic viruses (type 1)
• Vesicular stomatitis virus
• Visna virus
• Cytomegalovirus
• Epstein-Barr virus
• Influenza virus
• Pneumonovirus
• Sarcoma virus
• Syncytial virus
• Rubeola virus

 

[stellar]

I don't know enough to judge, but it's interesting. I don't think for a minute that vaccination is the only culprit, or perhaps even the main one. Mycoplasma can be everywhere!

And both Plague Time and Nicholson suggest that multiple factors (including environment) are likely involved.

I've seen the Tent videos and he does a pretty good job with the Mary's Monkey material - a book well worth the read.

Lots of dots in this big picture!

Well, I have to say that I'm pretty flabbergasted by the whole thing. I had NO IDEA that all of these things would come out in this topic. Heck, I was just looking for a treatment for a cluster of autoimmune conditions... When I first read about the amoeba protocol, I recalled what the Cs had said about parasitical infestation and mentioned it early in the thread. But, lordy mercy! I did not know it was going to be the can of worms it has proven to be. This is a whole new rabbit hole.

Yeah, talk about cutting edge research! I'm amazed that you've managed to find a huge part of the iron puzzle through this research. The fact that our bodies could be waging nutritional warfare against parasites puts the whole problem in an entirely new context. It also seems to be a big piece of the whole 4D/3D connection. To see that parasites could be critical for inter-density manipulation (and an astonishingly vast array of diseases) opens an entirely new realm of protection and "de-bugging". I'm finishing a few books, one on preparedness and the other being Personality Shaping, but I'm going to dive into Plague Time next. Absolutely astonishing stuff!

Certainly gives a whole new meaning to "the war being fought through us".

 

[Galaxia2002]

I usually use bromelain as anti inflammatory, it has a moderate effect as pain killer, and I found big differences between the effect that differents brands have on me. This is because the dose depends on the activity of the enzyme. So there are products that contain more mg of the enzyme and you could think that is better, but not. That activity is measured as GDU and should be specified in the product. A brand called ananase suggest use a charge dose and take it 3 times a day. I note the effects 8-12 hours after I take it.

Enzyme activity can also be given as that of certain standardized substrates, such as gelatin, then measured in gelatin digesting units (GDU), or milk proteins, then measured in milk clotting units (MCU). The units GDU and MCU are based on how fast one gram of the enzyme will digest gelatin or milk proteins, respectively. 1 GDU equals approximately 1.5 MCU.

_http://www.chiro.org/nutrition/ABSTRACTS/Bromelain.shtml

Bromelain is a general name for a family of sulfhydryl-containing, proteolytic enzymes obtained from Ananas comosus, the pineapple plant. Bromelain's primary component is a sulfhydryl proteolytic fraction. Bromelain also contains a peroxidase, acid phosphatase, several protease inhibitors, and organically-bound calcium. It appears a great deal of the physiological activity of bromelain cannot be accounted for by its proteolytic fraction and that the beneficial effects of bromelain are due to multiple factors, not to one single, isolated factor.

A variety of designations have been used to indicate the activity of bromelain, with published research varying in the designation utilized. Rorer units (r.u.), gelatin dissolving units (g.d.u.), and milk clotting units (m.c.u.) are the most commonly used measures of activity. One gram of bromelain standardized to 2000 m.c.u would be approximately equal to 1 gram with 1200 g.d.u. of activity or 8 grams with 100,000 r.u. of activity.

Pharmacokinetics Bromelain is absorbed intact through the gastrointestinal tract of animals, with up to 40 percent of the high molecular weight substances detected in the blood after oral administration. The highest concentration of bromelain is found in the blood one hour after administration; however, its proteolytic activity is rapidly deactivated. [1]

Mechanisms of Action

Bromelain's anti-inflammatory activity appears to be due to a variety of physiological actions. Evidence indicates that bromelain's action is in part a result of inhibiting the generation of bradykinin at the inflammatory site via depletion of the plasma kallikrein system, as well as limiting the formation of fibrin by reduction of clotting cascade intermediates. [2-4] Bromelain has also been shown to stimulate the conversion of plasminogen to plasmin, resulting in increased fibrinolysis. [4]

Bromelain might be capable of selectively modulating the biosynthesis of thromboxanes and prostacyclins, two groups of prostaglandins with opposite actions which ultimately influence activation of cyclic-3,5-adenosine, an important cell-growth modulating compound. It is hypothesized that bromelain therapy leads to a relative increase of the endogenous prostaglandins, PGI2 and PGE2 over thromboxane A2. [5]

Bromelain has been shown to decrease aggregation of blood platelets. [6] It is an effective fibrinolytic agent in vitro and in vivo; however, its effect is more evident in purified fibrinogen solutions than in plasma. [7]

Clinical Indications

Antitumor: Several studies, both animal and human, indicate bromelain might have some antimetastatic ability. [8-10] In doses of over 1000 mg daily, bromelain has been combined with chemotherapeutic agents such as 5-FU and vincristine, resulting in tumor regression. [8,11]

Immune Modulation: Bromelain can induce cytokine production in human peripheral blood mononuclear cells. Treatment leads to the production of tumor necrosis factor-alpha, interleukin-1-beta, and interleukin-6 in a time- and dose-dependent manner. [12,13] Bromelain has also been shown to remove T-cell CD44 molecules from lymphocytes and to affect T-cell activation. [14]

Debridement of Wounds: Bromelain applied topically as a cream (35% bromelain in a lipid base) can be beneficial in the elimination of burn debris and in acceleration of healing. [15] A non-proteolytic component of bromelain is responsible for this effect. This component, referred to as escharase, has no hydrolytic enzyme activity against normal protein substrates or various glycosaminoglycan substrates, and its activity varies greatly from preparation to preparation. [16]

Potentiation of Antibiotics: Antibiotic potentiation is one of the primary uses of bromelain in several foreign countries. In humans, some undetermined activity of bromelain has been documented to increase blood and urine levels of antibiotics. [17-19]

Combined bromelain and antibiotic therapy has been shown to be more effective than antibiotics alone in a variety of conditions including pneumonia, bronchitis, cutaneous staphylococcus infection, thrombophlebitis, cellulitis, pyelonephritis, perirectal and rectal abscesses, [20] and sinusitis. [21]

Mucolytic: In a clinical study of 124 patients hospitalized with chronic bronchitis, pneumonia, bronchopneumonia, bronchiectasis, or pulmonary abscess, those receiving bromelain orally showed a decrease in the volume and purulence of the sputum. [22]

Digestive Aid: Bromelain has been used successfully as a digestive enzyme following pancreatectomy, in cases of exocrine pancreas insufficiency, and in other intestinal disorders. [23] The combination of ox bile, pancreatin, and bromelain is effective in lowering stool fat excretion in patients with pancreatic steatorrhoea and resulting in a symptomatic improvement in pain, flatulence and stool frequency. [24]

Bromelain has been reported to heal gastric ulcers in experimental animals. [25] In an extensive study of the effect of bromelain on the gastric mucosa, it was found that bromelain increased the uptake of radioactive sulfur by 50 percent and glucosamine by 30-90 percent. Increased uptake of these substances may allow the gastric mucosa to heal more rapidly. [26]

Surgical Procedures and Musculoskeletal Injuries: Bromelain's most common application is in the treatment of inflammation and soft tissue injuries. It has been shown to speed healing from bruises and hematomas. [27] Treatment with bromelain following blunt injuries to the musculoskeletal system results in a clear reduction in swelling, pain at rest and during movement, and tenderness. [28] Administration of bromelain pre-surgically can reduce the average number of days for complete disappearance of pain and inflammation. [29,30]

Cardiovascular and Circulatory Applications: Research has indicated that bromelain prevents or minimizes the severity of angina pectoris. [31, 32] A drastic reduction in the incidence of coronary infarct after administration of potassium and magnesium orotate along with 120-400 mg of bromelain per day has been reported. [33] In a study involving 73 patients with acute thrombophlebitis, bromelain, in addition to analgesics, was shown to decrease all symptoms of inflammation; including, pain, edema, tenderness, skin temperature, and disability. [34]

One of the things that's supposed to be good for breaking up biofilms are anti-mucolytics, like NAC and guaifenesin -- they break down the mucal layer that allow the various microorganisms to adhere together, so that the organisms themselves are more vulnerable to treatment.

I found also that guaifenesin it is used in a protocol against fibromialgya

_https://en.wikipedia.org/wiki/Guaifenesin_protocol

I extract a quote:

History

This hypothesis arose when St. Amand noticed that patients with fibromyalgia symptoms had an increase of tartar on the teeth in the form of calcium phosphate. Crystals are also often found on urinalysis, which further points to calcium phosphate, and muscle biopsies show an steady state of phosphate in the cytosol as well as a dearth of ATP and phosphocreatine. The implication is that insufficient energy formation is the basis for the generalized cellular fatigue expressed in many tissues of fibromyalgia. Lesions of muscles, tendons, and ligaments can be felt by simple palpation. St. Amand calls this 'mapping' and uses it to confirm the diagnosis and in followup reversal of fibromyalgia. He feels that a genetically induced retention of phosphate also draws excess quantities of calcium into cells and exhorts them into overdrive. Contracted musculoskeletal tissues are the result and they produce the palpable lesions.

The treatment was discovered serendipitously when the physician found that uricosuric drugs for treating gout also coincided with relief of fibromyalgia symptoms. Guaifenesin is mildly uricosuric but, unlike standard uricosuric drugs, has almost no side-effects. here I found a relation with allopurinol then with mycoplasm? St. Amand therefore began to study whether guaifenesin might relieve the symptoms of fibromyalgia while causing fewer side-effects than the earlier medications.

Regarding herx reactions. According to my massage therapist ( and she is a very good one), she have treated some people with this reaction doing lymph drainage massage, with only one session of one hour the severity of symptoms are reduced almost entirely, so maybe the elimination system of the body needs some "mechanical" (not just chemical) help to get rid of the toxins.

 

[Gaby]

Regarding herx reactions. According to my massage therapist ( and she is a very good one), she have treated some people with this reaction doing lymph drainage massage, with only one session of one hour the severity of symptoms are reduced almost entirely, so maybe the elimination system of the body needs some "mechanical" (not just chemical) help to get rid of the toxins.

Yes, a nice massage would be nice in case of severe Herx reactions!

I noticed Garth Nicolson suggested monolaurin and/or lauric acid. Due to its energetic support and anti-microbial properties, it is a good one to keep in mind.

Another good thing on bromelain is its modulating effects on thromboxanes which you quoted above.

There was a testimonial from a moderator of prohealth.com that I quoted earlier in this thread. He did the protocol around 10 years ago and took doxycycline for 2 years and a half. He was on heparin, a mainstream medicine blood thinner. Apparently, a lot of debris and clotting agents (i.e. thromboxanes) get released as these parasites are dealt with. This is why I think it is important to include the vitamin E and any other natural blood thinner such as vitamin C and magnesium. Bromelain is certainly another to add for this mechanism of action.

 

[OneFielder]

A friend suggested I post on here. I'll admit, I concentrated on Laura's posts. She seems to be the one seeking to feel correct.

Wow, there's a sea of information. That's a problem. There's not directivity with reason really.

I'll point out that a million good things have been listed. And a million bad ones. But for whom?

Everything that aids in the balance of the bodies microbiome is important. However a healthy body that isn't deficient in development or with poor gene expression/mutation, shouldn't have a never ending, hiding, problem with microlife.

Which, I don't know but... if it is a microlife issue, I'll point out they typically don't solve themselves for a few reasons. The easiest one would be high blood sugar will certainly stop the immune system from properly functioning (diabetics get more infections for example), next is poor circulation (sinus/ear infection anyone?), and sometimes the immune system has no appropriate regulation so it doesn't discriminate properly (often influenced by GLA).

The inconsistency in relation to time, for straight just feeling well, leads me to believe that Laura's not achieving the goal, and possibly shouldn't even have the ones she does with current treatments. One cannot say she has the problems she believes for certain, based on the information. Also I wouldn't be able to confirm the believe that her intestinal permeability is well either (it's assumptive, it seems). There's a lot of faith here, looking for specifics in a system that may be compromised and providing subsequent side affects that get addressed back and forth. Granted there may be a more direct relational cause, but all too often it just isn't the case.

Anyway, since I've deconstructed what I see, I'd like to offer an opportunity to evaluate the overall status and be able to identify road blocks, misconceptions, and hopefully some solutions. But that would best start with asking a lot of question, of Laura, to start. If there's an interest in entertaining, I'm up for it. And as premature as this is, I'd point out that if one is concerned about lurking micolife then a blood thinner would be advisable for when circulation isn't well enough to work the body over. As an idea, bromelain (as mentioned) to lower inflammation and some nattokinase to thin blood may allow the immune system to deal with whatever species in remote locations. That would be a moot en-devour however say if one's intestines aren't well, or they have high blood sugar frequently. The root would just allow a continuation of the issue later.

 

[SeekinTruth]

Just to note, that the bio-weapons angle has been covered on this forum in a few long threads I've read years ago (including the work of the Scotts - father and son, if I remember correctly).

SeekinTruth, if you have a chance, would you be able to post the links to the threads you are thinking of so we can collect them in one place?

I did three searches just now and all came up with 0 results. Not even THIS thread comes up. Don't know what to make of it. I'll try again later and see what happens.

 

[Scottie]

A friend suggested I post on here. I'll admit, I concentrated on Laura's posts. She seems to be the one seeking to feel correct.

Wow, there's a sea of information. That's a problem. There's not directivity with reason really.

I'll point out that a million good things have been listed. And a million bad ones. But for whom?

Everything that aids in the balance of the bodies microbiome is important. However a healthy body that isn't deficient in development or with poor gene expression/mutation, shouldn't have a never ending, hiding, problem with microlife.

Welcome to the forum!

You should post an introduction here and tell a little bit about yourself.

As for this particular thread, since you are new to the forum, you are probably unaware of the many threads in our Diet and Health section. You are also most certainly unaware of the particular cases of Laura and many other forum members who have long-standing health issues.

In summary, this current thread of research, inquiry, and individual experimentation is not being done on a whim. It's the result of over 10 years of a whole lot of other research, inquiry, and individual dietary and health-related "adjustments".

We have many forum members who have had either long-term or short-term illnesses, ranging from minor bothersome infections, all the way up to full-blown aggressive cancers. I'm pretty sure that, considering many of these folks are happier, healthier, and still alive and well is testament to the efficacy of our seemingly "problematic" approach. People who should be dead are not, some who would have had bits of organs removed still have all their parts, etc. Sometimes traditional medical care works, sometimes one must push the boundaries. It's not a black and white situation - it's very much rainbow-colored. The same is true of our understanding of what works, and what doesn't - medically speaking. It can also be very specific to the individual.

For myself, I can say that I have been blessed with unusually good health for some odd reason. I've never had any serious illness or serious chronic condition, or even a cavity. Nevertheless, I'm still not totally devoid of some "health quirks". I have experimented with dietary changes and other methods, and I have still found dramatic improvements in my overall well-being. The reason I did so was because after reading and researching the topic, and after seeing the often surprising results that others saw, I figured what the heck? That was of course my choice, and not everybody will or needs to make that choice.

Now, certainly, this research and health "self-experiment" is not finished. I don't think all the answers have been found for specific health issues, or that there even is One True Answer. No one is really looking for such a thing, though. It's an ongoing process, and it happens to be focused right now on the possibilities surrounding a particular type of infection. Where will it lead? Who knows!

So, I think it's a bit premature for you to say that in Laura's particular case, she's "lost the plot" so to speak. There are many, many details that you are not aware of. As my favorite physicist is fond of saying: The devil is in the details!

Suffice it to say that all the things you pointed our in your post have already been taken into consideration. Of course, there was no way for you to know many of these things, but now you know!

 

[Foxx]

I usually use bromelain as anti inflammatory, it has a moderate effect as pain killer, and I found big differences between the effect that differents brands have on me. This is because the dose depends on the activity of the enzyme. So there are products that contain more mg of the enzyme and you could think that is better, but not. That activity is measured as GDU and should be specified in the product. A brand called ananase suggest use a charge dose and take it 3 times a day. I note the effects 8-12 hours after I take it.

If you've taken different brands and noted their different efficacy, do you have a brand that you recommend?

 

[lainey]

A friend suggested I post on here. I'll admit, I concentrated on Laura's posts. She seems to be the one seeking to feel correct.

Wow, there's a sea of information. That's a problem. There's not directivity with reason really.

I'll point out that a million good things have been listed. And a million bad ones. But for whom?

Everything that aids in the balance of the bodies microbiome is important. However a healthy body that isn't deficient in development or with poor gene expression/mutation, shouldn't have a never ending, hiding, problem with microlife.

Welcome to the forum!

You should post an introduction here and tell a little bit about yourself.

As for this particular thread, since you are new to the forum, you are probably unaware of the many threads in our Diet and Health section. You are also most certainly unaware of the particular cases of Laura and many other forum members who have long-standing health issues.

In summary, this current thread of research, inquiry, and individual experimentation is not being done on a whim. It's the result of over 10 years of a whole lot of other research, inquiry, and individual dietary and health-related "adjustments".

We have many forum members who have had either long-term or short-term illnesses, ranging from minor bothersome infections, all the way up to full-blown aggressive cancers. I'm pretty sure that, considering many of these folks are happier, healthier, and still alive and well is testament to the efficacy of our seemingly "problematic" approach. People who should be dead are not, some who would have had bits of organs removed still have all their parts, etc. Sometimes traditional medical care works, sometimes one must push the boundaries. It's not a black and white situation - it's very much rainbow-colored. The same is true of our understanding of what works, and what doesn't - medically speaking. It can also be very specific to the individual.

For myself, I can say that I have been blessed with unusually good health for some odd reason. I've never had any serious illness or serious chronic condition, or even a cavity. Nevertheless, I'm still not totally devoid of some "health quirks". I have experimented with dietary changes and other methods, and I have still found dramatic improvements in my overall well-being. The reason I did so was because after reading and researching the topic, and after seeing the often surprising results that others saw, I figured what the heck? That was of course my choice, and not everybody will or needs to make that choice.

Now, certainly, this research and health "self-experiment" is not finished. I don't think all the answers have been found for specific health issues, or that there even is One True Answer. No one is really looking for such a thing, though. It's an ongoing process, and it happens to be focused right now on the possibilities surrounding a particular type of infection. Where will it lead? Who knows!

So, I think it's a bit premature for you to say that in Laura's particular case, she's "lost the plot" so to speak. There are many, many details that you are not aware of. As my favorite physicist is fond of saying: The devil is in the details!

Suffice it to say that all the things you pointed our in your post have already been taken into consideration. Of course, there was no way for you to know many of these things, but now you know!

That would be a moot en-devour however say if one's intestines aren't well, or they have high blood sugar frequently.

The Ketogenic diet thread might be a nice place to start. Welcome!

 

[Galaxia2002]

I usually use bromelain as anti inflammatory, it has a moderate effect as pain killer, and I found big differences between the effect that differents brands have on me. This is because the dose depends on the activity of the enzyme. So there are products that contain more mg of the enzyme and you could think that is better, but not. That activity is measured as GDU and should be specified in the product. A brand called ananase suggest use a charge dose and take it 3 times a day. I note the effects 8-12 hours after I take it.

If you've taken different brands and noted their different efficacy, do you have a brand that you recommend?

the best I have taken is not available internationally, it is called ananase, in fact the pill is really tiny. That's the alternative to people that can't take NSAID. I have tried also source natural and it's not much powerful, and NOW food it is relatively good.

 

[DougEE]

Regarding herx reactions. According to my massage therapist ( and she is a very good one), she have treated some people with this reaction doing lymph drainage massage, with only one session of one hour the severity of symptoms are reduced almost entirely, so maybe the elimination system of the body needs some "mechanical" (not just chemical) help to get rid of the toxins.

Yes, a nice massage would be nice in case of severe Herx reactions!

I noticed Garth Nicolson suggested monolaurin and/or lauric acid. Due to its energetic support and anti-microbial properties, it is a good one to keep in mind.

Another good thing on bromelain is its modulating effects on thromboxanes which you quoted above.

There was a testimonial from a moderator of prohealth.com that I quoted earlier in this thread. He did the protocol around 10 years ago and took doxycycline for 2 years and a half. He was on heparin, a mainstream medicine blood thinner. Apparently, a lot of debris and clotting agents (i.e. thromboxanes) get released as these parasites are dealt with. This is why I think it is important to include the vitamin E and any other natural blood thinner such as vitamin C and magnesium. Bromelain is certainly another to add for this mechanism of action.

Thanks Gaby for this info on cooling Herx reactions. I only have myself and my wife to look at but from our vantage point our definition of a Herx reaction would be anxiety, dry mouth, hot sweats, nausea and sometimes diarrhea, oh and brain fog. Can you comment on what you would consider to be 'Herx reactions'?
Thanks

 

[Laura]

Thanks Gaby for this info on cooling Herx reactions. I only have myself and my wife to look at but from our vantage point our definition of a Herx reaction would be anxiety, dry mouth, hot sweats, nausea and sometimes diarrhea, oh and brain fog. Can you comment on what you would consider to be 'Herx reactions'?
Thanks

A strong Herx reaction is like the worst flu you ever had. Or like Dengue Fever, which I did have once.

 

[Mark]

And Also Xylitol (In this case used against oral biofilms)
http://www.ncbi.nlm.nih.gov/pubmed/19178100

PURPOSE:
The aim of the present study was to examine whether xylitol, at different concentrations, inhibits the formation of an experimental model of oral biofilm.
MATERIALS AND METHODS:
Biofilms of six bacterial species (Streptococcus mutans, Streptococcus sobrinus, Lactobacillus rhamnosus, Actinomyces viscosus, Porphyromonas gingivalis and Fusobacterium nucleatum) were prepared on hydroxyapatite (HA) discs according to the Zürich Biofilm Model. Xylitol was tested at two concentrations, 1% and 3%. At the end of their designated incubation times, some HA discs were destined for confocal laser scanning microscopy (CLSM) and the others were harvested using a sterile surgical instrument. Aliquots of harvested biofilms were diluted and plated onto specific media. After a 48-h anaerobic incubation at 37 degrees C, the colony-forming units (CFUs) were counted.
RESULTS:
CLSM images showed that only a small amount of isolated bacteria was observed on the surface of HA discs. Culture of harvested biofilms showed an inhibition in the growth of different species included in the biofilms.
CONCLUSIONS:
Xylitol has a clear inhibitory effect on the formation of the experimental biofilms. This study shows that xylitol is not only efficient in inhibiting the acid production of cariogenic bacteria, but also in preventing the formation of a multispecies biofilm; it confirms the relevance of the use of this polyol for the prevention of oral diseases caused by dental plaque.

Well, that's pretty interesting. Perhaps the reason some of us have issues with xylitol is that the mycoplasmas/biofilms react against it. Maybe that's one clue to those who have such infections: they have a reaction to xylitol???

And maybe Erythritol too, I remember some time back doing some research on making toothpaste and posting a link to a paper that stated erythritol as a substance that can break down biofilms, more effective at it than xylitol.

http://cassiopaea.org/forum/index.php/topic,32810.msg498985.html#msg498985

http://www.researchgate.net/publication/253332460_Erythritol_alters_microstructure_and_metabolomic_profiles_of_biofilm_composed_of_Streptococcus_gordonii_and_Porphyromonas_gingivalis

 

[Foxx]

the best I have taken is not available internationally, it is called ananase, in fact the pill is really tiny. That's the alternative to people that can't take NSAID. I have tried also source natural and it's not much powerful, and NOW food it is relatively good.

Thanks Galaxia2002!