From what I understand, Nattokinase is very easily / richly absorbed in the upper digestive trakt.
A Chinese study recently
has shown for example, that when taking 600 mg Nattokinase daily (300 mg in the morning, 300 mg in the evening / 3 pills each - on empty stomach), it gradually dissolves the plaque in our blood vessels over time to a high degree (while 100-200 mg didn't show any improvement) I have no link to the study. It was mentioned by old Grad daddy; Swedish Lars Bern (82), who often speaks about medical findings in the alternative media how people can improve / support their health.
What to watch out for, Bern says is, that you may get lower blood pressure to a degree that (in his case) he sometimes gets too low blood pressure (he then simply takes a break with Nattokinase for a while). Supposedly the condition of his blood vessels are now like "that of a 25 year old" A man who was very ill 30 years ago, on many strange medications that lead him on a path to nowhere and a lot more illnesses caused by Big Pharma's medications. Therefore, he became interested into investigating a lot more abouthealth, medicine, and studies.
Also to watch out for is kidney conditions and bleeding for those who are sensitive or have issues with it.
I personally take 600 mg Nattokinase since several weeks, because i have noticed that my left leg sometimes get somewhat thicker (puffy) compared to the other foot/lower leg - and socks leave a deeper mark in the skin. After weeks with Nattokinase however, my socks leave less pronounced marks, and seem to improve things.