Carl said:Yas said:It is about EDTA, but I think the same could be extrapolated to different chelators. It could be one of the reasons why some people don't do well when they start a heavy metal detox and develop an immune reaction that could be an infection, for example. Maybe some people need to address the stealth infections before doing any metal chelation.
Of course, another reason is that the person's detoxing organs and pathways might no be working so well, but stealth infections could aggravate while taking iodine for chelation without addressing that first, right?
There are many factors that can make a person feel really bad when detoxing metals, so that's another reason to read as much as posible about the subject so that one can identify different reactions and find out what they might be signaling.
I think EDTA is more commonly used for biofilm breaking and may have more of an effect in that regard. I haven't seen DMSA widely mentioned as helpful in biofilms. Also the dosages with DMSA are generally lower and more spaced out. Maybe avoiding EDTA is a good idea if you just want to tackle heavy metals first and foremost.
Seems you're right:
[quote author=https://www.researchgate.net/publication/11067306_Anti_microbial_activity_of_dimercaptosuccinic_acid_DMSA_a_new_chelating_agent]
Successful outcome of endodontic treatment depends on elimination of bacteria and their products present in the root canal. It has been reported that after careful chemicomechanical preparation, smear layer is formed on the walls of canal, which contains bacteria and their products. Chelating agents, when used during chemicomechanical preparation, remove the smear layer. DMSA--a new chelating agent, when used in root canals, removes the smear layer more than EDTA when used as irrigant in root canals. This study was conducted to determine whether DMSA has anti microbial activity and compare it with EDTA. The results show that EDTA (10% & 15%) had marked anti microbial activity, both on culture plates and in broth. DMSA (10% & 15%) did not show anti microbial activity on culture plates while in broth it had marked activity.[/quote]
Looks like DMSA is good for pulling metals but is not as good as EDTA for breaking up the biofilms themselves, if I'm reading this correctly.